DL-2-Pyrrolidone-5-Carboxylic Acid
DL-Pyroglutamic acid
CAS: 149-87-1
Molecular Formula: C5H7NO3
DL-2-Pyrrolidone-5-Carboxylic Acid - Names and Identifiers
| Name | DL-Pyroglutamic acid |
| Synonyms | H-Dl-Pyr-Oh Dl-5-Oxoproline 5-oxo-L-proline 5-OXO-DL-PROLINE 5-Oxo-Dl-Proline Dl-Proline, 5-Oxo- DL-Proline, 5-oxo- DL-PYROGLUTAMIC ACID DL-Pyroglutamic acid DL-A-PYROGLUTAMIC ACID Dl-A-Pyroglutamic Acid DL-GLUTAMIC ACID LACTAM Dl-Glutamic Acid Lactam 2-PYRROLIDONE-5-CARBOXYLIC ACID 2-Pyrrolidone-5-Carboxylic Acid DL-2-Pyrrolidone-5-Carboxylic Acid |
| CAS | 149-87-1 |
| EINECS | 205-748-3 |
| InChI | InChI=1/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1 |
| InChIKey | ODHCTXKNWHHXJC-UHFFFAOYSA-N |
DL-2-Pyrrolidone-5-Carboxylic Acid - Physico-chemical Properties
| Molecular Formula | C5H7NO3 |
| Molar Mass | 129.11 |
| Density | 1.3816 (rough estimate) |
| Melting Point | 183-185°C(lit.) |
| Boling Point | 239.15°C (rough estimate) |
| Flash Point | 227.8°C |
| Water Solubility | 5.67 g/100 mL (20 ºC) |
| Solubility | 5.67 g/100 mL (20 °C) |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | White crystalline powder |
| Color | White |
| BRN | 82131 |
| pKa | 3.48±0.20(Predicted) |
| PH | 1.7 (50g/l, H2O, 20℃) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Hygroscopic |
| Refractive Index | 1.4220 (estimate) |
| MDL | MFCD00064322 |
| Use | Mainly used as biochemical reagents |
DL-2-Pyrrolidone-5-Carboxylic Acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29337900 |
| Hazard Class | IRRITANT |
DL-2-Pyrrolidone-5-Carboxylic Acid - Study on the combined toxicity of quorum sensing inhibitor, sulfamethoxazole and doxycycline hydrochloride to Escherichia coli and its mechanism
from VIP
Abstract:
quorum sensing inhibitor (QSIs) has the characteristics of no resistance, which is used as a possible alternative to antibiotics, has broad application prospects, therefore, there is the possibility of combined exposure with traditional antibiotic environment, but there is still a lack of related joint effects. In this paper, Escherichia coli (Escherichia coli) as the test organism, seven QSIs(DL-pyroglutamic acid ,N-vinylpyrrolidone, furanone acetate, 2-methyltetrahydrofuran-3-one, 3, 4-dibromo-2 (5h)-furanone,(R) the combined toxicity of 3-pyrrolidinol and D-prolinol with sulfamethoxazole (SMX) and doxycycline hydrochloride (DH) was investigated. According to the analysis of the results, the first 5 QSIs act on the quorum sensing system mediated by AI-2 signaling molecules, and compete with the AI-2 signaling molecules to bind Lsr B protein, the action pathway of DH does not affect each other, so the combined effect is additive; The latter two QSIs act on the quorum sensing system mediated by AI-1 class signaling molecules, and compete with AI-1 class signaling molecules to bind to Sdi protein A, however, the effects of SMX and DH may stimulate the expression of Sdi A protein, so that more QSIs should be consumed to bind to Sdi A, so the combined effect is antagonistic. This study can provide a theoretical basis for the ecological risk assessment of the combined exposure of traditional antibiotics and QSIs.
stowed
Key words:
quorum sensing inhibitor sulfamethoxazole doxycycline hydrochloride E. Coli Joint toxicity
DOI:
10.7524/AJE.1673-5897.20160903001
year:
2017
Last Update：2024-01-02 23:10:35
DL-2-Pyrrolidone-5-Carboxylic Acid - Amino acid-containing water-soluble fertilizer with bactericidal effect and preparation method thereof
from Baidu Library
patent type:
invention patent
Application (patent) number:
CN201710470878.5
application date:
20170620
Public/Announcement Number:
CN107235769A
Public/announcement date:
20171010
applicant (patent):
Emeishan Longteng Biotechnology Co., Ltd.
inventor:
National and provincial code:
CN511181
Abstract:
The invention belongs to the technical field of fertilizer processing, in particular to an amino acid-containing water-soluble fertilizer with bactericidal effect and a preparation method thereof, the amino acid-containing water-soluble fertilizer of the present invention uses DL pyroglutamic acid waste as a raw material, adds a variety of Chinese herbal medicine components, and carries out an appropriate ratio, the amino acid-containing water-soluble fertilizer has a significant bactericidal effect, while ensuring the nutrient needs in the whole growth process of crops, the prevention and control of diseases and insect pests in advance, and the possibility of plant diseases is significantly reduced, thereby reducing the use of pesticides. In addition, the present invention also provides a new way of recycling DL pyroglutamic acid. The produced water-soluble fertilizer containing amino acid is also a completely water-soluble fertilizer, and its nutrient elements are comprehensive, easy to be absorbed by crops, can be used for chlorine, calcium, magnesium fertilizer crops, especially suitable for tomato, cotton, rice, wheat and corn.
Last Update：2024-01-02 23:10:35
DL-2-Pyrrolidone-5-Carboxylic Acid - Introduction
Solubility in water: 5 · 67% (20°C), soluble in ethanol and acetone.
Last Update：2022-10-16 17:14:04
DL-2-Pyrrolidone-5-Carboxylic Acid - Reference Information
| LogP | 0.065 at 21.1℃ |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| use | mainly used as biochemical reagent |
Last Update：2024-04-09 21:54:55
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